RecruitingPhase 1 / Phase 2NCT07325136

A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer

The purpose of this study is to assess the safety and tolerability of BMS-986525 alone and in combination with Pumitamig in participants with Relapsed/Refractory Small Cell Lung Cancer

Checked against the public recordLast updated Aug 18, 2026 · Source: ClinicalTrials.gov

StatusRecruiting
PhasePhase 1 / Phase 2
U.S. locations13
SponsorBristol-Myers Squibb
01
Study overview

What this study is about

Purpose
Treatment
Study type
Interventional
Phase
Phase 1 / Phase 2
Sponsor
Bristol-Myers Squibb
Interventions being studied
Drug: BMS-986525; Drug: Pumitamig
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

Inclusion Criteria * Participants must have histologically or cytologically documented relapsed/refractory small cell lung cancer (R/R-SCLC). * Participants must have received at least 1 platinum-based chemotherapy regimen as per locally approved drug labels and institutional guidelines. * In countries where standard of care first line systemic treatment includes platinum containing chemotherapy in combination with anti-PD-(L)1 therapy, it is required that participants have progressed on, are ineligible for or not have access to an anti-PD- (L)1 therapy. Exclusion Criteria * Participants must not have any untreated CNS metastases. * Participants must not have an active, known or suspected autoimmune disease. * Participants must not have had a prior organ or tissue allograft. * Other protocol-defined Inclusion/Exclusion criteria apply.

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Karmanos Cancer InstituteDetroit, Michigan
  • Local Institution - 0026Buffalo, New York
  • Duke Cancer InstituteDurham, North Carolina
  • University Hospitals Cleveland Medical CenterCleveland, Ohio
  • SCRI Oncology PartnersNashville, Tennessee
  • Local Institution - 0029Beijing, Beijing Municipality
  • Local Institution - 0028Shanghai Shi, Shanghai Municipality
  • Istituto Clinico HumanitasRozzano, Milano
  • Local Institution - 0020Hirakata, Osaka
  • Local Institution - 0018Chuo-ku, Tokyo
  • Oncohelp Medical CenterTimișoara, Timiș County
  • Centrul de Oncologie Sf. Nectarie SRLCraiova

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Aug 18, 2026. Always confirm current availability with the study team.

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