A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer
The purpose of this study is to assess the safety and tolerability of BMS-986525 alone and in combination with Pumitamig in participants with Relapsed/Refractory Small Cell Lung Cancer
Checked against the public recordLast updated Aug 18, 2026 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Treatment
- Study type
- Interventional
- Phase
- Phase 1 / Phase 2
- Sponsor
- Bristol-Myers Squibb
- Interventions being studied
- Drug: BMS-986525; Drug: Pumitamig
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
Inclusion Criteria * Participants must have histologically or cytologically documented relapsed/refractory small cell lung cancer (R/R-SCLC). * Participants must have received at least 1 platinum-based chemotherapy regimen as per locally approved drug labels and institutional guidelines. * In countries where standard of care first line systemic treatment includes platinum containing chemotherapy in combination with anti-PD-(L)1 therapy, it is required that participants have progressed on, are ineligible for or not have access to an anti-PD- (L)1 therapy. Exclusion Criteria * Participants must not have any untreated CNS metastases. * Participants must not have an active, known or suspected autoimmune disease. * Participants must not have had a prior organ or tissue allograft. * Other protocol-defined Inclusion/Exclusion criteria apply.
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- Karmanos Cancer InstituteDetroit, Michigan
- Local Institution - 0026Buffalo, New York
- Duke Cancer InstituteDurham, North Carolina
- University Hospitals Cleveland Medical CenterCleveland, Ohio
- SCRI Oncology PartnersNashville, Tennessee
- Local Institution - 0029Beijing, Beijing Municipality
- Local Institution - 0028Shanghai Shi, Shanghai Municipality
- Istituto Clinico HumanitasRozzano, Milano
- Local Institution - 0020Hirakata, Osaka
- Local Institution - 0018Chuo-ku, Tokyo
- Oncohelp Medical CenterTimișoara, Timiș County
- Centrul de Oncologie Sf. Nectarie SRLCraiova
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Aug 18, 2026. Always confirm current availability with the study team.