7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

Study summary

Comparison of a 7t MRI to standard of care 1.5t/3t MRI scans to determine if earlier detection of brain metastases are possible on a 7t.

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Key things to know

Main goalNot specified

This describes the study’s primary purpose.

What is being studied7t MRI

The study team can explain what participation involves.

Who it may be forSmall cell lung cancer (SCLC)

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Dec 2, 2025 · Source: ClinicalTrials.gov

Is enrollment open?Recruiting

The study is currently accepting participants.

What kind of study?Not applicable

Observational

Where is it offered?1 U.S. location

Locations may change over time.

Who runs it?University of Missouri-Columbia

Study sponsor

Study overview

What this study is about

Purpose: Not specified
Study type: Observational
Phase: Not applicable
Sponsor: University of Missouri-Columbia
Interventions being studied: Device: 7t MRI

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How this study is categorized

These labels come from structured fields and exact terms in the public record.

Cancer type

Small cell lung cancer (SCLC)→

Study topics

Brain metastases→

Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria

Patient must have a histologically confirmed diagnosis of small-cell lung cancer (SCLC).
Patient must have an MRI of the brain, performed within 4 weeks prior to consent, documenting no evidence of brain metastases or leptomeningeal disease.
Patient also must not have a history of brain metastases or leptomeningeal disease.
Patient must refuse PCI and agree to surveillance with brain MRI scans (1.5T/3T).
Patient must be ≥ 18 years of age.
Patient must have ECOG Performance Status of 0-2
Patients must be able to tolerate the 7T MRI

Reasons someone may not be able to joinExclusion criteria

Patient must not have a contraindication to an MRI, such as implanted metal devices or foreign bodies.
Patient must not have a contraindication to gadolinium contrast administration during MR imaging.
Patient must not have other metastatic malignancies requiring current active treatment.
Pregnant patients are excluded. Pregnancy status will be confirmed verbally.

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

Study sites

U.S. locations

University of MissouriColumbia, Missouri

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Dec 2, 2025. Always confirm current availability with the study team.

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