TerminatedNot applicableNCT06513663
Official study title

Exercise as Maintenance Therapy in Advanced Lung Cancer

Study summary

The purpose of this study is to examine how a multimodality (having or using a variety of methods to do something) exercise intervention may improve survival, function, and quality of life in participants with advanced lung cancer.

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Key things to know

Main goalSupportive Care

This describes the study’s primary purpose.

What is being studiedExercise Intervention

The study team can explain what participation involves.

Who it may be forNon-small cell lung cancer (NSCLC) · Metastatic or stage IV

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Apr 27, 2026 · Source: ClinicalTrials.gov

Is enrollment open?Terminated

Ask the study team to confirm whether enrollment is open.

What kind of study?Not applicable

Interventional

Where is it offered?3 U.S. locations

Locations may change over time.

Who runs it?Indiana University

Study sponsor

01
Study overview

What this study is about

Purpose
Supportive Care
Study type
Interventional
Phase
Not applicable
Sponsor
Indiana University
Interventions being studied
Behavioral: Exercise Intervention
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria

1. Age ≥ 18 years 2. Known diagnosis of locally advanced (stage III) or metastatic NSCLC 3. Patient is currently receiving maintenance immunotherapy for at least 1 month and planned for at least 3 additional months of therapy 1. Patients receiving maintenance therapy refers to patients with stable disease or partial response to therapy, including patients who have had a history of disease progression but are currently stable or responding to a different therapy 2. Patients previously receiving chemotherapy are eligible as long as at least one month has elapsed since completing chemotherapy. Those currently receiving chemotherapy are not eligible. 4. Patient is willing and able to participate in a supervised home-based exercise program as determined by the MOVE program a.Participants must have internet access and equipment to participate in virtual exercise 5. ECOG performance status of 0-2

Reasons someone may not be able to joinExclusion criteria
  • 1. Already meeting exercise guidelines and participating in at least 150 minutes of moderate or vigorous exercise per IPAQ 2. Unable to participate in the supervised home-based exercise program as determined by the MOVE program 3. Medical co-morbidities that preclude patient from participating in supervised exercise, including but not limited to:
  • Advanced heart failure
  • Advanced respiratory disease requiring home oxygen use
  • Uncontrolled psychiatric disorders
  • History of fragility fracture

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Indiana University Health Methodist HospitalIndianapolis, Indiana
  • Indiana University Melvin & Bren Simon Comprehensive Cancer CenterIndianapolis, Indiana
  • Sidney and Lois Eskenazi HospitalIndianapolis, Indiana

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Apr 27, 2026. Always confirm current availability with the study team.

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