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RecruitingNot applicableNCT06432985
Official study title

Smoking Cessation CM for Veterans With or at Risk for Cancer

Study summary

Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping Veterans quit smoking during lung cancer screening or cancer care at VA clinics. CM is a behavioral treatment that uses rewards to encourage smoking cessation when verified through biological testing. In the first year, the researchers will develop a mobile CM protocol based on feedback from Veterans and healthcare staff through focus groups. In the second year, they will conduct a pilot study to test the feasibility of the mobile CM program along with counseling and medication for 20 Veterans over a five-week period. The success of the pilot study will determine whether to proceed with a larger randomized controlled trial (RCT) in years three to six, comparing the efficacy of mobile CM with standard treatment. The project will take place at SFVA.

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Key things to know

Main goalTreatment

This describes the study’s primary purpose.

What is being studiedFocus Group and Contingency Management (CM)

Plus 1 other study approaches.

Who it may be forTobacco Use Disorder · Substance Use Disorder

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Oct 2, 2026 · Source: ClinicalTrials.gov

Is enrollment open?Recruiting

The study is currently accepting participants.

What kind of study?Not applicable

Interventional

Where is it offered?1 U.S. location

Locations may change over time.

Who runs it?VA Office of Research and Development

Study sponsor

01
Study overview

What this study is about

Purpose
Treatment
Study type
Interventional
Phase
Not applicable
Sponsor
VA Office of Research and Development
Interventions being studied
Behavioral: Focus Group; Behavioral: Contingency Management (CM); Behavioral: TUD Treatment as Usual (TAU)
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

Treatment approach
Supportive or behavioral care→
03
Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria
  • In order to be eligible to participate in this study, an individual must meet all of the following criteria:
  • Human Subjects Involvement and Characteristics: This Proof of Concept and Clinical Trial has three stages. The Proof-of-Concept Phase (Years 1-2) includes a Focus Group phase (Year 1) in which the investigators will recruit both Veterans and non-Veterans (VA clinical staff); and a Pilot Study (Year 2) in which the investigators will recruit Veterans in LCS or cancer treatment at San Francisco VA Healthcare System (SFVAHCS). If the Pilot Study is successful, the investigators will recruit Veterans in lung cancer screening (LCS) or cancer treatment for the RCT (Years 3-6).
  • Focus Groups: For Focus Groups (Year 1), the investigators will recruit both Veterans and VA clinical staff at SFVAHCS. Veterans:
  • Veteran eligible for VA healthcare
  • English-speaking
  • Received SFVAHCS cancer monitoring or treatment or lung cancer screening (LCS) within the past 24 months
  • Active cigarette smoking within the past 24 months
  • Have access to Wi-Fi and a device that supports audio and video communication VA Clinical Staff:
  • Current member of clinical staff at the SFVAHCS
  • Have participated in the care of at least 5 VA cancer or LCS patients in the past 6 months Pilot Feasibility Study (Year 2) and Randomized Controlled Trial Inclusion criteria:
  • Veteran currently receiving medical care at SFVAHCS (at least one clinical visit same calendar year for cancer)
  • English-speaking
  • Current, active (same calendar year) enrollment in VA LCS, or current (same calendar year) diagnosis of cancer documented in the VA medical record, confirmed through medical record review
  • Current (past 30 days) cigarette smoking a minimum of 1 cigarette per day (average), assessed by Timeline Followback (TLFB)92, 99-101
  • Open to receiving smoking cessation interventions
Reasons someone may not be able to joinExclusion criteria

Focus Groups: For Focus Groups (Year 1), the investigators will recruit both Veterans and VA clinical staff at SFVAHCS. Veterans:

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • San Francisco VA Medical Center, San Francisco, CASan Francisco, California

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Oct 2, 2026. Always confirm current availability with the study team.

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