Tobacco Cessation at FDNY
At the Fire Department of the City of New York (FDNY) World Trade Center Health Program, 36% of participants in the low dose computed tomography (LDCT) lung cancer screening program are current smokers, despite referral to the free FDNY Tobacco Cessation Program (Standard Care). Investigators propose testing an Enhanced Care program which includes opt-out enrollment; tobacco cessation counseling will be individually tailored to spirometry/LDCT results and treatment with varenicline starting 4 weeks prior to their target quit date. This randomized trial will compare enrollment and cessation outcomes in Standard Care vs. Enhanced Care groups of challenging-to-treat, high-risk smokers.
Checked against the public recordLast updated Jan 29, 2026 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Treatment
- Study type
- Interventional
- Phase
- Phase 4
- Sponsor
- Albert Einstein College of Medicine
- Interventions being studied
- Other: opt out enrollment, tailored counseling, varenicline started prior to target quit date; Other: opt in enrollment, non-tailored counseling, varenicline started prior to target quit date
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
Inclusion Criteria * Enrolled in FDNY World Trade Center Health Program (WTCHP) * Retired * Age ≥ 50 years old * Self-reported current smoker on most recent questionnaire OR self-reported current smoker in the past 5 years * 20 pack-year smoker OR 20-year smoking duration Exclusion Criteria * Reduced renal function * estimated glomerular filtration rate (eGFR) \<30 \[CKD-EPI Creatinine Equation (2021)\] at last World Trade Center (WTC) medical monitoring blood exam OR ICD10 codes for kidney disease: N04.9, N17.9, N18.9, Z94.0, E13.21, N18.9, I12.9, N00.9, N03.9 * Undergoing active cancer treatment, defined as being diagnosed on 1/1/2022 or later * Clinical instability (e.g., hospitalization in last 3 months) * Using varenicline in last 30 days * Endorsing suicidal ideations: moderate or high risk on Columbia-Suicide Severity Rating Scale (C-SSRS) * Screened for alcohol use disorder AUDIT\>15
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- FDNY World Trade Center Health ProgramBrooklyn, New York
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Jan 29, 2026. Always confirm current availability with the study team.