TerminatedPhase 2NCT05577715

A Study of MORAb-202 in Participants With Previously Treated Metastatic Non-Small Cell Lung Cancer (NSCLC) Adenocarcinoma (AC)

The aim of this study is to characterize the safety and tolerability of MORAb-202, and to assess the objective response rate in participants with previously treated, metastatic NSCLC AC.

Checked against the public recordLast updated Sep 4, 2025 · Source: ClinicalTrials.gov

StatusTerminated
PhasePhase 2
U.S. locations33
SponsorBristol-Myers Squibb
01
Study overview

What this study is about

Purpose
Treatment
Study type
Interventional
Phase
Phase 2
Sponsor
Bristol-Myers Squibb
Interventions being studied
Drug: MORAb-202
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

Inclusion Criteria: * Histologically or cytologically documented metastatic NSCLC AC (as defined by the 8th International Association for the Study of Lung Cancer Classification). * Measurable target disease assessed by the investigator according to RECIST 1.1. * Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0 or 1 Exclusion Criteria: * NSCLC histologies other than AC (ie, squamous cell carcinoma, large cell carcinoma). * Significant third-space fluid retention (eg, ascites or pleural effusion) that requires repeated drainage. * Prior pneumonectomy. Prior lobectomy and segmentectomy are allowed \> 12 months before treatment. * Recent chest radiotherapy. Participants with chest or chest wall radiation may be permitted if chest radiation is documented \> 6 months before starting study treatment. Other protocol-defined inclusion/exclusion criteria apply.

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Local Institution - 0007Orange, California
  • Local Institution - 0035Lone Tree, Colorado
  • Local Institution - 0043Clermont, Florida
  • Local Institution - 0010Orange City, Florida
  • Local Institution - 0001Marietta, Georgia
  • Local Institution - 0005Louisville, Kentucky
  • Local Institution - 0044Silver Spring, Maryland
  • Henry Ford HospitalDetroit, Michigan
  • Local Institution - 0002Kansas City, Missouri
  • Local Institution - 0011Charlotte, North Carolina
  • Local Institution - 0034Arlington, Texas
  • Local Institution - 0045Flower Mound, Texas

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Sep 4, 2025. Always confirm current availability with the study team.

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