Near-Infrared Perfusion During Minimally Invasive Thoracic Surgery Download

Study summary

This will be a prospective, (NSR), single-center feasibility study of the Olympus VE2 NIR Imaging System to assess perfusion using NIR during minimally invasive esophagectomy and pulmonary segmentectomy. The aims of the study are: 1\. To utilize NIR intraoperative imaging with the Olympus VE2 NIR Imaging System to: i. Characterize gastric conduit perfusion during esophagectomy and, ii. Identify segmental anatomy during sublobar pulmonary resection (segmentectomy) after intraoperative, intravenous delivery of low-dose 0.15 mg/kg of ICG.

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Key things to know

Main goalOther

This describes the study’s primary purpose.

What is being studiedOlympus VE2 NIR Imaging System and Indocyanine green

The study team can explain what participation involves.

Who it may be forLung Neoplasms · Esophageal Lesion

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Nov 26, 2025 · Source: ClinicalTrials.gov

Is enrollment open?Completed

Ask the study team to confirm whether enrollment is open.

What kind of study?Phase 1 / Phase 2

Interventional

Where is it offered?1 U.S. location

Locations may change over time.

Who runs it?Massachusetts General Hospital

Study sponsor

Study overview

What this study is about

Purpose: Other
Study type: Interventional
Phase: Phase 1 / Phase 2
Sponsor: Massachusetts General Hospital
Interventions being studied: Device: Olympus VE2 NIR Imaging System; Drug: Indocyanine green

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How this study is categorized

These labels come from structured fields and exact terms in the public record.

Treatment approach

Surgery→

Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria

Subject has a suspicious lung lesion for which a minimally invasive segmentectomy is planned -OR- sub-ject has an esophageal lesion for which an esophagectomy is planned -
Subject is 18 years of age or older
Subject is willing and able to provide informed consent

Reasons someone may not be able to joinExclusion criteria

Subject is not eligible for surgical resection as determined by the treating physician
Subject has known or suspected allergy to Iodine, shellfish or intravenous contrast
Subject is not eligible or considered high risk for surgical resection as determined by pre-operative spirometry
Subject is female and of childbearing age who is currently pregnant or who is planning to become pregnant within the study
Subject is unable and unwilling to provide informed consent
Subject has liver disease or is taking drugs impact liver metabolism.

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

Study sites

U.S. locations

Massachusetts General HospitalBoston, Massachusetts

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Nov 26, 2025. Always confirm current availability with the study team.

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