Virtual Trial to Compare Two Digital Therapeutics as Interventions for Physical and Mental Health in People With Cancer

Inclusion Criteria: * Stage I-III cancer diagnosis * Currently in active systemic treatment of chemotherapy, radiation or immunotherapy, have completed systemic treatment within the past 6 months, or have a treatment plan including planned systemic treatment. * Are experiencing at least moderate anxiety * 18 years of age or older * Are fluent in English * Have access to a smartphone (a mobile phone that performs many of the functions of a computer, typically having a touchscreen interface, internet access, and an operating system capable of running downloaded applications) or tablet that runs iOS or Android software, with cellular data service or wifi access. * Willing to download software onto smartphone or tablet from Apple store or Android store Exclusion Criteria: * Systemic treatment plan includes only endocrine therapy. * Treatment plan includes stem cell/bone marrow transplant. * Currently participating in any other investigative CBT trial for treatment of anxiety or depression. * Participant is unable to complete training, has cognitive deficits, more severe psychiatric conditions, lack of access to internet accessible device or psycho-social conditions (e.g., other social conditions, that would interfere with adherence to self-directed care), such that in investigator's opinion the participant would be unable to complete the study * Recently completed use of Blue Note Therapeutics Covid Cancer Care Program or other Blue Note Therapeutics device or Blue Note Therapeutics-sponsored study * Are experiencing severe levels of depression OR indicate suicidal risk (measured by surveys during screening for the study) * Are experiencing anxiety below the required level (measured by a survey during screening for the study) * Cancer diagnosis is melanoma, multiple myeloma, unstaged cancer.