Neoadjuvant Immunotherapy in Advanced NSCLC
A number of clinical trials have demonstrated the efficacy of immunotherapy prior as neoadjuvant therapy. This study evaluates whether said neoadjuvant immunotherapy may improve improve progression free survival in NSCLC. One such example would be to evaluate either single agent or an immunotherapy combination with chemotherapy. Following this, analysis of biomarkers will be conducted to provide personalization in one's regimen.
Checked against the public recordLast updated Feb 7, 2022 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Not specified
- Study type
- Observational
- Phase
- Not applicable
- Sponsor
- Power Life Sciences Inc.
- Interventions being studied
- Biological: Immunotherapy
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
Inclusion Criteria: * \>= 18 Years of Age * Informed consent is provided * Histologically confirmed resectable non-small cell lung cancer with stage II-IIIA (TNM 8th edition) * Eastern Cooperative Oncology Group (ECOG) performance status 0-1 * Epidermal growth factor receptor (EGFR) mutation negative and anaplastic lymphoma kinase (ALK) translocation negative Exclusion Criteria: * EGFR mutation positive and ALK translocation positive * Active central nervous system (CNS) metastases * Autoimmune diseases * Inhaled or topical steroids, and adrenal replacement steroid doses \> 10 mg daily prednisone equivalent, are permitted in the absence of active autoimmune disease * Patients with interstitial lung disease will not be included if they have symptomatic interstitial lung disease (ILD) - Grade 3-4 * Women who are breast feeding or pregnant * Sexually active women or men of childbearing potential who are not willing to use an effective contraceptive method during the study
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- Power Life SciencesSan Francisco, California
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Feb 7, 2022. Always confirm current availability with the study team.