Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening

Study summary

To compare the effectiveness of four interventions to promote sustained, biochemically confirmed smoking abstinence for 6 months among underserved smokers referred for lung cancer screening at four large U.S. health systems.

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Key things to know

Main goalTreatment

This describes the study’s primary purpose.

What is being studiedRemoval of Financial Barriers and Financial Incentives

Plus 1 other study approaches.

Who it may be forSmoking Cessation

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Feb 25, 2026 · Source: ClinicalTrials.gov

Is enrollment open?Completed

Ask the study team to confirm whether enrollment is open.

What kind of study?Not applicable

Interventional

Where is it offered?5 U.S. locations

Locations may change over time.

Who runs it?Abramson Cancer Center at Penn Medicine

Study sponsor

Study overview

What this study is about

Purpose: Treatment
Study type: Interventional
Phase: Not applicable
Sponsor: Abramson Cancer Center at Penn Medicine
Interventions being studied: Behavioral: Removal of Financial Barriers; Behavioral: Financial Incentives; Behavioral: Mobile Health Application

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How this study is categorized

These labels come from structured fields and exact terms in the public record.

Treatment approach

Supportive or behavioral care→

Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria

Current smoker (≥ 1 cigarettes per day, not including e-cigarettes)
Has a low-dose computed tomography (LDCT) scan ordered by their physician
Underserved, defined as one or more of the following: (a) Black, (b) Hispanic, (c) rural residence, or (d) low socioeconomic status (Defined as one or both of: high-school education or less, or household income \<200% of the federal poverty line)
Able to receive study invitation and screening, by virtue of showing up to a radiology location affiliated with a participating health system for the LDCT, or having a valid email address or telephone number on file with the health system
Access to a cell phone with text messaging or the internet
Aged 18 years or older

Reasons someone may not be able to joinExclusion criteria

No cell phone

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

Study sites

U.S. locations

Kaiser Permanente Southern CaliforniaOakland, California
Henry Ford Health SystemDetroit, Michigan
GeisingerDanville, Pennsylvania
Lancaster General HealthLancaster, Pennsylvania
University of PennsylvaniaPhiladelphia, Pennsylvania

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Feb 25, 2026. Always confirm current availability with the study team.

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