Safety of Lung Cryobiopsy in People With Cancer
The purpose of this study is to find out whether a biopsy technique called transbronchial cryobiopsy (TBCB) is a safe alternative to the standard biopsy procedure (transbronchial forceps biopsy; TBFB). The study researchers think that TBCB may provide better biopsy samples to help diagnose lung disease.
Checked against the public recordLast updated Jul 1, 2026 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Diagnostic
- Study type
- Interventional
- Phase
- Phase 2
- Sponsor
- Memorial Sloan Kettering Cancer Center
- Interventions being studied
- Procedure: Transbronchial cryobiopsy
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
Inclusion Criteria: * 18 years of age or greater * Patients with known or suspected diagnosis of cancer and indeterminant pulmonary nodules or diffuse parenchymal lung disease with non-diagnostic clinical profiles for whom a lung biopsy is deemed useful for diagnosis. Exclusion Criteria: * Patients with pulse oximetry less than 92% on oxygen delivery up to 2 L nasal cannula. * Uncorrectable coagulopathy defined as: * Platelet count \<50,000 x 10\^9/L or * prothrombin time international normalized ratio \>1.5 * Known pulmonary hypertension or echocardiographic pulmonary artery systolic pressure \>50mmHg * A secure diagnosis based on clinical and high-resolution CT scan data. * Antiplatelet therapy that cannot be held for more than 5 days. * Any patient deemed unfit to undergo bronchoscopy by the proceduralist * Female patients with a positive pregnancy test within 30 days of the planned study procedure
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Jul 1, 2026. Always confirm current availability with the study team.