Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer

Study summary

This phase II trial studies how well respiratory muscle training before surgery works in preventing lung complications after surgery in patients with stage I-IIIB lung cancer. Patients with lung cancer who choose to undergo surgical resection often have complications after surgery such as pneumonia, unplanned intubations, difficulty breathing and reduced physical functioning, and increased medical costs and a reduced quality of life. Improving pre-surgical pulmonary health through respiratory muscle training may improve respiratory muscle strength, response to surgery, and quality of life after surgery in patients with lung cancer.

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Key things to know

Main goalPrevention

This describes the study’s primary purpose.

What is being studiedBest Practice and Laparoscopic Surgery

Plus 4 other study approaches.

Who it may be forEarly-stage or resectable

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated May 18, 2026 · Source: ClinicalTrials.gov

Is enrollment open?Recruiting

The study is currently accepting participants.

What kind of study?Phase 2

Interventional

Where is it offered?1 U.S. location

Locations may change over time.

Who runs it?Roswell Park Cancer Institute

Study sponsor

Study overview

What this study is about

Purpose: Prevention
Study type: Interventional
Phase: Phase 2
Sponsor: Roswell Park Cancer Institute
Interventions being studied: Other: Best Practice; Procedure: Laparoscopic Surgery; Other: Quality-of-Life Assessment; Other: Questionnaire Administration; Device: Respiratory Muscle Training Device; Procedure: Video-Assisted Thoracic Surgery

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How this study is categorized

These labels come from structured fields and exact terms in the public record.

Disease setting

Early-stage or resectable→

Treatment approach

Surgery→

Study topics

Before surgery (neoadjuvant)→After surgery (adjuvant)→Survivorship and quality of life→

Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria

Documented stage I-IIIb lung cancer or is undergoing surgery for diagnosis
Participant is able to speak, read, and comprehend English
Participant must be undergoing or is anticipated to either video-assisted thoracic surgery (VATS or robotic surgery) or laparoscopic surgery for curative intent lung resection
Patients with or without neoadjuvant chemoradiotherapy (CRT) prior to surgery will be included
Ability to follow written and verbal instructions
Participant must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure

Reasons someone may not be able to joinExclusion criteria

Documented ischemic heart disease; congestive heart failure or; significant cardiac arrhythmias that would exclude them from having surgery
Overall medical frailty (clinician discretion) or ECOG \> 2
Pregnant or nursing female participants
Unwilling or unable to follow protocol requirements
Any condition which in the investigator's opinion deems the participant an unsuitable candidate to participate in this study

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

Study sites

U.S. locations

Roswell Park Cancer InstituteBuffalo, New York

Source and freshness
Processed from ClinicalTrials.gov. Last public update: May 18, 2026. Always confirm current availability with the study team.

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