Active Not RecruitingPhase 3NCT03815643

Avelumab Program Rollover Study

The main purpose of this study is to monitor the safety and tolerability of avelumab in participants with solid tumors who continue treatment with avelumab under the same treatment regimen as in the parent avelumab study.

Checked against the public recordLast updated Jun 29, 2026 · Source: ClinicalTrials.gov

StatusActive Not Recruiting
PhasePhase 3
U.S. locations104
SponsorEMD Serono Research & Development Institute, Inc.
01
Study overview

What this study is about

Purpose
Treatment
Study type
Interventional
Phase
Phase 3
Sponsor
EMD Serono Research & Development Institute, Inc.
Interventions being studied
Drug: Avelumab
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

Inclusion Criteria: * Participants under enrollment and treatment in an avelumab clinical study under the sponsorship of EMD Serono Research \& Development Institute, Inc. / Merck KGaA, Darmstadt, Germany * Merck Serono Co., Ltd (Japan) * Participants currently enrolled in an avelumab parent study and are on active treatment with avelumab or in long-term survival follow-up after treatment * Participants on active treatment must agree to continue to use highly effective contraception (that is, methods with a failure rate of less than 1% per year) for both male and female participants if the risk of conception exists * Other protocol defined inclusion criteria could apply. Exclusion Criteria: * Participants who are pregnant or breastfeeding * Participants still on active treatment: Known hypersensitivity to any of the study intervention ingredients * Participant has been enrolled in the comparator arm of avelumab parent study * Participant has been withdrawn from avelumab parent study for any reason * Any other reason that, in the opinion of the Investigator, precludes the participant from participating in the study * Other protocol defined exclusion criteria could apply.

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • HonorHealth Research InstituteScottsdale, Arizona
  • Highlands Oncology GroupFayetteville, Arkansas
  • University of California Davis Health System - Comprehensive Cancer CenterSacramento, California
  • Providence Medical FoundationSanta Rosa, California
  • St Joseph Heritage HealthcareSanta Rosa, California
  • Norwalk Hospital - The Whittingham Cancer CenterNorwalk, Connecticut
  • Hematology - Oncology Associates of the Treasure Coast - Hematology-Oncology Associates of Treasure CoastPort Saint Lucie, Florida
  • Northwest Georgia Oncology CentersMarietta, Georgia
  • Maryland Oncology Hematology, P.A.Rockville, Maryland
  • Michigan State UniversityLansing, Michigan
  • Virginia Piper Cancer InstituteMinneapolis, Minnesota
  • Kansas City Research Institute, LLC - Phase I UnitKansas City, Missouri

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Jun 29, 2026. Always confirm current availability with the study team.

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