Understanding the Post-Surgical Non-Small Cell Lung Cancer Patient's Symptom Experience

Study summary

Among 13 core symptoms across 3,106 breast, colorectal, prostate, and lung cancer patients, persons with lung cancer were the most symptomatic, with moderate to severe fatigue being reported with the greatest prevalence. This is a proposed randomized controlled trial of a novel rehabilitative intervention for persons with non-small cell lung cancer after surgery that promotes self-management of cancer-related fatigue (CRF) and is practical, portable, low cost, and safe. The results of the study will provide a novel exercise intervention, and its optimal timing, that helps a vulnerable population by reducing CRF severity and fatigability and is applicable to nearly all post-thoracotomy lung cancer patients.

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Key things to know

Main goalOther

This describes the study’s primary purpose.

What is being studiedLight Physical Activity 1 and Light Physical Activity 2

Plus 1 other study approaches.

Who it may be forNon-small cell lung cancer (NSCLC)

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Feb 24, 2026 · Source: ClinicalTrials.gov

Is enrollment open?Completed

Ask the study team to confirm whether enrollment is open.

What kind of study?Not applicable

Interventional

Where is it offered?1 U.S. location

Locations may change over time.

Who runs it?University of Nebraska

Study sponsor

Study overview

What this study is about

Purpose: Other
Study type: Interventional
Phase: Not applicable
Sponsor: University of Nebraska
Interventions being studied: Behavioral: Light Physical Activity 1; Behavioral: Light Physical Activity 2; Behavioral: Support Education Activity

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How this study is categorized

These labels come from structured fields and exact terms in the public record.

Cancer type

Non-small cell lung cancer (NSCLC)→

Treatment approach

Surgery→Supportive or behavioral care→

Study topics

After surgery (adjuvant)→Survivorship and quality of life→

Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria

Women and men
At least 18 years of age (Michigan) and 19 years of age in (Nebraska)
With suspected non-small cell lung cancer to be confirmed after surgery
Karnofsky Performance Status score of at least 70%
Thoracic surgeon approval pre- and post-surgery
Medically stable comorbid conditions allowing for non-small cell lung cancer surgery clearance
Has phone access capability
Able to speak and write English
Able to hear and speak for phone interviews
Owns a television
Lives within 2 hours driving distance of recruitment site

Reasons someone may not be able to joinExclusion criteria

Severe impairment of sight, hearing, speaking
Active treatment for malignancy within past 3 months (other than non-melanoma skin cancer or long-term hormonal treatment for common cancers such as breast and prostate if disease is stable
Weight greater than 330 pounds
History of photosensitive seizures
Any condition or disorder that would impede safe participation as directed
Plans to relocate outside the area during the study period or unable to fully participate

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

Study sites

U.S. locations

University of Nebraska Medical CenterOmaha, Nebraska

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Feb 24, 2026. Always confirm current availability with the study team.

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