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TerminatedNot applicableNCT03403361
Official study title

Dual-Energy CT on Plan Quality, Dose-delivery Accuracy, and Simulated Outcomes of Patients Treated With Proton or Photon Therapy

Study summary

The aim of this protocol is to refine the accuracy of proton beam therapy (PT) by the use of dual energy computed tomography (DECT), in conjunction with novel iterative image reconstruction algorithms, to more precisely determine the tissue properties through which the proton beam path travels.

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Key things to know

Main goalDiagnostic

This describes the study’s primary purpose.

What is being studiedSiemens Somatom Definition Edge and Philips Brilliance Big Bore CT/simulator

The study team can explain what participation involves.

Who it may be forLung Cancer · Brain Cancer

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Mar 1, 2024 · Source: ClinicalTrials.gov

Is enrollment open?Terminated

Ask the study team to confirm whether enrollment is open.

What kind of study?Not applicable

Interventional

Where is it offered?1 U.S. location

Locations may change over time.

Who runs it?Washington University School of Medicine

Study sponsor

01
Study overview

What this study is about

Purpose
Diagnostic
Study type
Interventional
Phase
Not applicable
Sponsor
Washington University School of Medicine
Interventions being studied
Device: Siemens Somatom Definition Edge; Device: Philips Brilliance Big Bore CT/simulator
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria
  • Eligibility Criteria:
  • Diagnosis of histologically proven primary or metastatic cancer requiring thoracic radiation therapy OR radiation therapy to the head and neck or brain
  • At least 18 years of age.
  • Planning to undergo proton or photon beam radiation therapy as part of the clinical management of the diagnosed cancer.
  • Able to understand and willing to sign an IRB-approved written informed consent document.
Reasons someone may not be able to joinExclusion criteria
  • Implanted metallic objects in the region to be scanned excepting dental prostheses
  • IV or oral contrast medium within 24 hours prior to DECT image acqusition
  • Pregnant.

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Washington University School of MedicineSt Louis, Missouri

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Mar 1, 2024. Always confirm current availability with the study team.

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