A Safety Study of Nivolumab in Combination With Ipilimumab in Participants With Advanced Non-small Cell Lung Cancer
A Study to Evaluate Safety in Participants with Chemotherapy-naïve Stage IV or Recurrent Non-small Cell Lung Cancer Treated With Nivolumab in Combination with Ipilimumab
Checked against the public recordLast updated Apr 17, 2018 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Treatment
- Study type
- Interventional
- Phase
- Phase 3
- Sponsor
- Bristol-Myers Squibb
- Interventions being studied
- Drug: Nivolumab; Drug: Ipilimumab
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: * 1\) Stage IV or recurrent non-Small cell lung cancer * 2\) Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-1 * 3\) Prior adjuvant or neoadjuvant chemotherapy for local, advanced disease allowed if completed at least 6 months prior to randomization Exclusion Criteria: * 1\) Known epidermal growth factor receptor (EGFR) mutations or anaplastic lymphoma syndrome(ALK) translocations that are sensitive to targeted inhibitor therapy * 2\) Active, known or suspected autoimmune disease or HIV infection * 3\) Prior treatment with any drug that targets T cell co-stimulation pathways (such as checkpoint inhibitors) * 4\) Untreated Central Nervous System metastases Other protocol defined inclusion/exclusion criteria could apply
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- Local InstitutionSan Francisco, California
- Local InstitutionLincoln, Nebraska
- Local InstitutionHackensack, New Jersey
- Local InstitutionColumbus, Ohio
- Local InstitutionLancaster, Pennsylvania
- Local InstitutionLanghorne, Pennsylvania
- Local InstitutionSayre, Pennsylvania
- Local InstitutionCharleston, South Carolina
- Local InstitutionSt. George, Utah
- Local InstitutionViedma, Río Negro Province
- Local InstitutionMontreal, Quebec
- Local InstitutionDresden
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Apr 17, 2018. Always confirm current availability with the study team.