WithdrawnPhase 2NCT03029416

Two Radiation Dose Schedules of SBRT to Lung Metastases < 5cm in Dimension

30 Gy single fraction of SBRT for lung metastases will result in comparable oncologic outcomes to 18Gy in three fractions (or dosing to a BED \</-100Gy at the discretion of the radiation oncologist) with respect to disease control and toxicity.

Checked against the public recordLast updated Oct 15, 2018 · Source: ClinicalTrials.gov

StatusWithdrawn
PhasePhase 2
U.S. locations1
SponsorRonald McGarry
01
Study overview

What this study is about

Purpose
Treatment
Study type
Interventional
Phase
Phase 2
Sponsor
Ronald McGarry
Interventions being studied
Radiation: Stereotactic Body Radiation Therapy
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

Treatment approach
03
Public criteria

Who may be able to participate

Inclusion Criteria: * Histological confirmation of malignant carcinoma/sarcoma (any site) with metastasis to lung. * Patients must not be eligible for therapy with curative intent (i.e. surgery, radiation, etc). * Patients must have measurable disease, defined as at least one lesion that can be accurately measured in at least one dimension * Age ≥18 years * ECOG performance status \>/= 2 (Karnofsky≥60%)). * Ability to understand and the willingness to sign a written informed consent document. Exclusion Criteria: * Patients with more than \>/=3 metastatic lung lesions or any one lesion greater than 5 cm. and/or extensive metastatic disease outside the chest. * Patients who are receiving any other investigational agents. * Patients with active systemic, pulmonary, or pericardial infection. * Pregnant or lactating women * Patients with known brain metastases should be excluded from this clinical trial because of their poor prognosis and because they often develop progressive neurologic dysfunction that would confound the evaluation of neurologic and other adverse events. * Uncontrolled inter-current illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements. * Chemotherapy concurrent with SBRT is not allowed

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • University of KentuckyLexington, Kentucky

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Oct 15, 2018. Always confirm current availability with the study team.

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