Mesenchymal Stem Cells (MSCs) for Treatment of Acute Respiratory Distress Syndrome (ARD) in Patients With Malignancies

Inclusion Criteria: 1. ARDS characterized by hypoxemia and bilateral radiographic opacities not fully explained by cardiac failure or fluid overload as judged by the treating physician using all available data. Moderate ARDS includes patients with malignancies with the previous presentation and a P/F ratio \</= 200 or SF ratio of \</= 214. The duration of the hypoxemia criterion and the radiograph criterion must be within 10 days of the time of enrollment. 2. Patients age \>/=18 years. 3. Treated with appropriate maximal medical therapy for pulmonary toxicity. 4. Negative pregnancy test in a woman with childbearing potential defined as not post-menopausal for 12 months or no previous surgical sterilization. 5. Patient or legally appropriate proxy must be able to understand study instructions and sign consent. Exclusion Criteria: 1. Unstable ventricular tachycardia or fibrillation. 2. Moribund patients not expected to survive up to 48 hours. 3. Patients with ARDS resulting from trauma. 4. Patients with documented deep venous thrombosis or pulmonary embolism within the past 3 months. 5. Patients with severe chronic liver disease (Childs-Pugh score \> 10). 6. Patients with previous solid organ transplant. 7. Pregnant and/or lactating women.