CompletedPhase 1NCT02000947

A Phase 1b Study of MEDI4736 in Combination With Tremelimumab in Subjects With Advanced Non-small Cell Lung Cancer

The purpose of this study is to determine if MEDI4736 will be adequately tolerated in combination with tremelimumab in subjects with advanced non-small cell lung cancer (NSCLC).

Checked against the public recordLast updated Oct 31, 2019 · Source: ClinicalTrials.gov

StatusCompleted
PhasePhase 1
U.S. locations69
SponsorMedImmune LLC
01
Study overview

What this study is about

Purpose
Treatment
Study type
Interventional
Phase
Phase 1
Sponsor
MedImmune LLC
Interventions being studied
Drug: MEDI4736; Drug: Tremelimumab; Drug: tremelimumab
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

Inclusion Criteria: 1. Age ≥ 18 years 2. Advanced non-small cell lung cancer 3. Eastern Cooperative Oncology Group (ECOG) performance status of 0-1 4. Adequate organ and marrow function Exclusion Criteria: 1. Any concurrent chemotherapy, immunotherapy, biologic, or hormonal therapy for cancer treatment 2. Current or prior use of immunosuppressive medication within 14 days before the first dose of study drugs 3. Active or prior documented autoimmune disease within the last 2 years.

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Research SiteBirmingham, Alabama
  • Research SiteTucson, Arizona
  • Research SiteLos Angeles, California
  • Research SiteLos Angeles, California
  • Research SiteSan Francisco, California
  • Research SiteAurora, Colorado
  • Research SiteNew Haven, Connecticut
  • Research SiteNewark, Delaware
  • Research SiteTampa, Florida
  • Research SiteIndianapolis, Indiana
  • Research SiteBaltimore, Maryland
  • Research SiteBoston, Massachusetts

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Oct 31, 2019. Always confirm current availability with the study team.

View original record ↗