Pilot Study: Utilizing Manometry to Assess Radiation-Induced Changes in Esophageal Function

Inclusion Criteria: * Age ≥ 18 years or older * Absence of any severe disorders of esophageal motility (patients with reflux and/or a hiatal hernia are eligible) * Histologically confirmed lung cancer scheduled to undergo conventionally fractionated radiation treatment * Patients that will be treated with a minimum of 45 Gy of radiation therapy * Patients with mediastinal nodal disease, or primary lesions that are near the esophagus are eligible provided that they are not having esophageal symptoms believed to be due to the tumor. Exclusion Criteria: * History of esophageal motility disorder that pre-dates and is unrelated to the present diagnosis of lung cancer * History of any prior radiotherapy to the esophagus * Pregnant or lactating women * Inability to understand and follow swallowing instructions for the esophageal manometry procedure; this is to ensure patient compliance of performing the breath hold technique throughout the radiation therapy treatment * Patients with mediastinal nodal disease, or primary lesions, that are having esophageal symptoms believed to be due to the tumor