CompletedNot applicableNCT01896778

Body Warming in Improving Blood Flow and Oxygen Delivery to Tumors in Patients With Cancer

This randomized pilot clinical trial studies body warming in improving blood flow and oxygen delivery to tumors in patients with cancer. Heating tumor cells to several degrees above normal body temperature may kill tumor cells.

Checked against the public recordLast updated Jul 25, 2022 · Source: ClinicalTrials.gov

StatusCompleted
PhaseNot applicable
U.S. locations1
SponsorRoswell Park Cancer Institute
01
Study overview

What this study is about

Purpose
Basic Science
Study type
Interventional
Phase
Not applicable
Sponsor
Roswell Park Cancer Institute
Interventions being studied
Procedure: Hyperthermia Treatment; Other: Laboratory Biomarker Analysis
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

Inclusion Criteria: * Patients with a variety of malignancies (i.e., melanoma, sarcoma, colon, head and neck, renal, breast, lung, ovary, liver) * Patients must have measurable disease (1.0 cm or greater) by computed tomography (CT) scan * Have an estimated glomerular filtration rate (eGFR) (using the Cockcroft-Gault equation) of more than 60 mL/min * Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2 * Patients of child-bearing potential must agree to use acceptable contraceptive methods (e.g., double barrier) during treatment * Patient or legal representative must understand the investigational nature of this study and sign an Independent Ethics Committee/Institutional Review Board approved written informed consent form prior to receiving any study related procedure Exclusion Criteria: * History of prior myocardial infarction or arrhythmia * History of any condition deemed by the principal investigator to be a contraindication to B-WARM therapy (e.g., skin reaction, dysregulation of thermoregulation, etc) * All patients with transdermal patches (e.g.; fentanyl, Lidoderm, scopolamine, etc) * Pregnant or nursing female patients * Unwilling or unable to follow protocol requirements * Any condition which in the investigator's opinion deems the patient an unsuitable candidate to receive B-WARM * Received an investigational agent within 30 days prior to enrollment * Received any systemic therapy within 21 days prior to planned B-WARM therapy * Patients may be enrolled on study but at least 21 days should elapse prior to date of B-WARM therapy * Patients should not have either CT scanning or B-WARM if they have a fever at the time * Fever should be worked up and treated as appropriate * Patients should be afebrile for 24 hours prior to scanning or B-WARM therapy

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Roswell Park Cancer InstituteBuffalo, New York

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Jul 25, 2022. Always confirm current availability with the study team.

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