Chest Imaging, Breath, and Biomarkers in a Screening Trial
The investigators would like to see if lung cancer screening with chest x-rays,computer aided detection (CAD)and a lose dose CT scan can detect lung cancer in early stages when it is more responsive to treatment. The investigators would also like to see if early detection will reduce the incidence of symptomatic advanced lung cancer compared to no screening in former and current smokers with or without a family history of lung cancer who are 40-75 years old.
Checked against the public recordLast updated May 18, 2017 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Not specified
- Study type
- Observational
- Phase
- Not applicable
- Sponsor
- The Cleveland Clinic
- Interventions being studied
- Device: chest x-ray with or without CAD, lose dose CT scan
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
Inclusion Criteria: * ages 40-75 years * If ages 40-59, then one of the following criteria needs to be met: * Current or ex-smoker with \>25 pack years and a family history of lung cancer(parent or sibling) OR * current or ex-smoker with \> 25 pack years and COPD OR * current or ex-smoker with a \> 35 pack year history * If ages 60-75, then one of the following additional criteria needs to be met: * Current or ex-smoker with \>25 pack years and a family history of lung cancer (parent or sibling) OR * Current or ex-smoker with \>25 pack years and COPD OR * Current or ex-smoker with a \>30 pack year history * Subject is able to return to Cleveland Clinic for annual follow-up screening * Subject is willing to sign a medical release form Exclusion Criteria: * Current health requires oxygen * Have had a chest x-ray or CT of the chest within the last 6 months * Previous pneumonectomy * Lobectomy of the lung within the last 5 years * Diagnosed malignancy within the last 5 years, excluding non-melanoma skin cancer, carcinoma in situ of the cervix and localized prostate cancer * A medical condition that would prevent treatment for lung cancer * Within the last 6 weeks, one of the following has occured: * A new cough or chronic cough that has gotten worse * Either new shortness of breath, or any worsening of shortness of breath * A cough producing blood * Constant chest pain * Respiratory infection, pneumonia, or cold * Unintentional and unexplained weight loss greater than 5% of total body weight
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- Cleveland ClinicCleveland, Ohio
Source and freshness
Processed from ClinicalTrials.gov. Last public update: May 18, 2017. Always confirm current availability with the study team.