Regional Anesthesia and Lung Cancer Recurrence

Study summary

Test the effect of combined regiona/general anesthesia on lung cancer recurrence compared to general anesthesia alone.

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Key things to know

Main goalSupportive Care

This describes the study’s primary purpose.

What is being studiedGeneral-epidural anesthesia and Balanced general anesthesia and postoperative opioids

The study team can explain what participation involves.

Who it may be forRecurrent or relapsed

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Sep 15, 2016 · Source: ClinicalTrials.gov

Is enrollment open?Terminated

Ask the study team to confirm whether enrollment is open.

What kind of study?Not applicable

Interventional

Where is it offered?2 U.S. locations

Locations may change over time.

Who runs it?The Cleveland Clinic

Study sponsor

Study overview

What this study is about

Purpose: Supportive Care
Study type: Interventional
Phase: Not applicable
Sponsor: The Cleveland Clinic
Interventions being studied: Other: General-epidural anesthesia; Other: Balanced general anesthesia and postoperative opioids

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How this study is categorized

These labels come from structured fields and exact terms in the public record.

Disease setting

Recurrent or relapsed→

Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria

Primary non-small cell lung cancer (stage 1-3) as determined according to the IASLC Lung Cancer Staging Project;
Scheduled for potentially curative tumor resection;
Written informed consent, including willingness to be randomized to epidural anesthesia/analgesia plus general anesthesia or to general anesthesia and postoperative opioid analgesia.

Reasons someone may not be able to joinExclusion criteria

Any contraindication to epidural anesthesia, (including coagulopathy, abnormal anatomy).
Any contraindication to midazolam, propofol, sevoflurane, fentanyl, morphine, or hydromorphone.
Age \< 18 or \> 85 years old.
Other cancer not believed by the attending surgeon to be in long-term remission.

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

Study sites

U.S. locations

Cleveland ClinicCleveland, Ohio
Shanghai Chest HospitalShanghai

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Sep 15, 2016. Always confirm current availability with the study team.

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