Stanford Accelerated Recovery Trial (START)
The goal of this study is to determine whether administering Gabapentin prior to surgery affects duration of pain and opioid use post-surgery. The investigators aim to compare gabapentin to placebo in a prospective, randomized clinical trial in which patients will be followed post-surgery until pain resolves and opioid use ceases.
Checked against the public recordLast updated May 5, 2022 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Supportive Care
- Study type
- Interventional
- Phase
- Phase 3
- Sponsor
- Stanford University
- Interventions being studied
- Drug: Gabapentin; Drug: Lorazepam (active control); Drug: Placebo (inactive)
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
INCLUSION CRITERIA * Age 18 to 75 * Undergoing a scheduled surgery * English speaking * Ability and willingness to complete questionnaires or use Palm Pilot EXCLUSION CRITERIA * Known kidney disease * Currently receiving gabapentin or (pregabalin) lyrica already * Cognitive impairment * Previous history of excessive sedation or adverse reaction to gabapentin (not it was tried but ineffective for nerve pain) * Coexisting chronic pain \> 4/10 disorder in area other than surgical target * Plan to move out of state * Condition that would in judgment of team member make patient likely to be lost to follow-up * Elevated suicidality * Known pregnancy * Current symptoms of ataxia, dizziness, or sedation * Narrow angle glaucoma * Severe respiratory insufficiency (ie, severe emphysema or chronic obstructive pulmonary disease) * History of gastric bypass surgery and obstructive sleep apnea requiring continuous positive airway pressure (CPAP)
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- Stanford University School of MedicineStanford, California
Source and freshness
Processed from ClinicalTrials.gov. Last public update: May 5, 2022. Always confirm current availability with the study team.