CompletedNot applicableNCT00899028

Identifying Biomarkers for Lung Cancer Using Tissue Samples From Patients With Lung Cancer and From Healthy Participants

RATIONALE: Studying samples of tissue, blood, sputum, and urine from patients with lung cancer and from healthy participants in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at biomarkers for lung cancer using tissue samples from patients with lung cancer and from healthy participants.

Checked against the public recordLast updated Apr 20, 2017 · Source: ClinicalTrials.gov

StatusCompleted
PhaseNot applicable
U.S. locations4
SponsorVanderbilt University Medical Center
01
Study overview

What this study is about

Purpose
Not specified
Study type
Observational
Phase
Not applicable
Sponsor
Vanderbilt University Medical Center
Interventions being studied
Genetic: comparative genomic hybridization; Genetic: fluorescence in situ hybridization; Genetic: gene expression analysis; Genetic: microarray analysis; Genetic: protein expression analysis; Other: immunohistochemistry staining method; Other: laboratory biomarker analysis; Other: matrix-assisted laser desorption/ionization time of flight mass spectrometry; Other: medical chart review; Procedure: diagnostic bronchoscopy
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

DISEASE CHARACTERISTICS: * Meets 1 of the following criteria: * Known or previously diagnosed lung cancer * Suspected lung cancer, including the following: * Completely resected stage I lung cancer (with no evidence of metastatic disease) for which patient is at risk for developing secondary disease * Suspected of having lung cancer due to clinical symptoms, such as positive sputum cytology, hemoptysis, unresolved pneumonia, persistent cough, and positive x-ray * Healthy volunteer PATIENT CHARACTERISTICS: * WBC ≥ 2,000/mm³ but ≤ 20,000/mm³ * Platelet count ≥ 50,000/mm³ * Not pregnant * No uncontrolled hypertension (i.e., systolic blood pressure \> 200 mm Hg, diastolic blood pressure \> 120 mm Hg) * No unstable angina * No known bleeding disorder * No other contraindications for white light bronchoscopic examination * No other contraindications for fluorescence examination PRIOR CONCURRENT THERAPY: * More than 3 months since prior fluorescent photosensitizing agents (hematoporphyrin derivatives) * More than 3 months since prior and no concurrent chemopreventative drugs (e.g., tretinoin) * More than 6 months since prior ionizing radiation treatment to the chest * More than 6 months since prior systemic cytotoxic chemotherapy * No concurrent anticoagulant therapy

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Vanderbilt-Ingram Cancer Center - Cool SpringsNashville, Tennessee
  • Vanderbilt-Ingram Cancer Center at FranklinNashville, Tennessee
  • Veterans Affairs Medical Center - NashvilleNashville, Tennessee
  • Vanderbilt-Ingram Cancer CenterNashville, Tennessee

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Apr 20, 2017. Always confirm current availability with the study team.

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