Losartan in Treating Patients With Idiopathic Pulmonary Fibrosis
RATIONALE: Losartan may be effective in treating patients with idiopathic pulmonary fibrosis. PURPOSE: This clinical trial is studying the side effects of losartan and to see how well it works in treating patients with idiopathic pulmonary fibrosis.
Checked against the public recordLast updated Feb 21, 2021 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Treatment
- Study type
- Interventional
- Phase
- Not applicable
- Sponsor
- University of South Florida
- Interventions being studied
- Drug: losartan
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
INCLUSION CRITERIA: * Age \> 21 years * Diagnosis of idiopathic pulmonary fibrosis * Patients taking Coumadin and/or N-acetylcysteine may participate in the study * Baseline forced vital capacity (FVC) must be greater than or equal to 50% * Baseline 6 minute walk test distance walked must be greater than or equal to 200 meters not requiring greater than 6 lpm of oxygen EXCLUSION CRITERIA: * Pregnant, intending to become pregnant or breastfeeding * Current or previous smoker of cigarettes or marijuana that recently quit within the last 6 months prior to enrollment * Allergy or allergic reaction to Losartan or any other angiotensin II receptor blocker * Taking losartan or any other angiotensin II receptor blocker * Baseline systolic blood pressure \< 100 mmHg * Currently taking or has taken immunosuppressant agents within the last month such as azathioprine, cyclophosphamide, colchicine and/or prednisone * History of lung transplant * History of kidney failure or liver disease * Inability to attend clinic visits
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- University of CincinnatiCincinnati, Ohio
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Feb 21, 2021. Always confirm current availability with the study team.