Proton Therapy for Stage I Non-Small Cell Lung Cancer (LU03)
This is a research study to determine if hypofractionated image guided radiation therapy (hypoIGRT) with proton therapy is a good way to treat early stage lung tumors for patients who will not have surgery. HypoIGRT delivers higher daily doses of radiation over a shorter period of time compared with conventional radiation. This is thought to deliver a more lethal dose of radiation to the tumor and is more convenient with treatment being completed within 2-3 weeks compared to the typical 7-8 week course of conventional radiotherapy.
Checked against the public recordLast updated Mar 24, 2022 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Treatment
- Study type
- Interventional
- Phase
- Not applicable
- Sponsor
- University of Florida
- Interventions being studied
- Radiation: Peripherally located lung tumor; Radiation: Centrally located lung tumor
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
Inclusion Criteria: * Pathologically confirmed, by biopsy or cytology, non-small cell lung carcinoma diagnosed within 3 months prior to study enrollment. * T1, N0, M0 or T2, N0, M0. (AJCC Lung 7th Edition) * At least 18 years old at the time of consent. * Adequate bone marrow function. * Medically inoperable. Medically operable candidates are allowed if they refuse surgical resection. * If the patient has a large pleural effusion, it must be biopsy negative. Exclusion Criteria: * Evidence of distant metastasis (M1) and/or nodal involvement (N1, N2, N3). * Synchronous primary. * T2 tumors \> 5 cm; T3, T4 primary tumor. * Previous radiotherapy for lung cancer. * Concomitant local, regional, and/or systemic therapy during radiotherapy. * Active systemic, pulmonary, and/or pericardial infection.
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- University of Florida Proton Therapy InstituteJacksonville, Florida
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Mar 24, 2022. Always confirm current availability with the study team.