S0720: Adjuvant Therapy Based on Gene Expression in Stage IA and IB Non-Small Cell Lung Cancer

DISEASE CHARACTERISTICS: * Histologically confirmed non-small cell lung cancer * Stage IA (longest tumor diameter 2-3 cm) or stage IB disease * Must have undergone preoperative CT scan of the chest (including the entire liver and adrenals) with IV contrast AND a whole body PET scan or a combined PET/CT scan with no evidence of N1, N2, N3, or M1 disease within 42 days prior to surgery * A whole body PET scan or a combined PET/CT must be performed within 84 days * Any finding on PET scan that clinically suggests N1, N2, N3, or M1 disease must have been cleared by further evaluation, including, but not limited to, any of the following: * Ultrasonography, X-ray radiology, magnetic resonance imaging, or nuclear medicine imaging * Completely resected (R0) disease by lobectomy, bilobectomy, or pneumonectomy performed by open thoracotomy or video-assisted thoracoscopic surgery within the past 35 days * Completely excised primary lesion with negative gross and microscopic margins * At least two mediastinal lymph node stations sampled * Must have tumor tissue available from the surgical resection specimen AND agree to have treatment assignment determined by a gene expression analysis performed on that tissue PATIENT CHARACTERISTICS: * Zubrod performance status 0-1 * ANC ≥ 1,500/mm³ * Platelet count ≥ 100,000/mm³ * Hemoglobin ≥ 10 mg/dL * Serum bilirubin ≤ 1.5 times upper limit of normal (ULN) * AST and ALT ≤ 1.5 times ULN * Serum creatinine ≤ 1.5 times ULN OR creatinine clearance ≥ 60 mL/min * Not pregnant or nursing * Fertile patients must use effective contraception * No other prior malignancy except for the following: * Adequately treated basal cell or squamous cell skin cancer * In situ cervical cancer * Adequately treated stage I-II cancer from which the patient is currently in complete remission * Any other cancer from which the patient has been disease-free for 5 years * Willing to provide prior smoking history PRIOR CONCURRENT THERAPY: * See Disease Characteristics * No prior systemic chemotherapy or biologic therapy for lung cancer * No prior thoracic radiation therapy (RT) (including RT to the chest wall) * No other concurrent investigational agents, chemotherapeutic agents, RT, or hormonal therapy * Steroids administered for antiemesis, adrenal failure, or septic shock OR hormones administered for non-disease-related conditions (e.g., insulin for diabetes) allowed