DNA Repair and Genetic Susceptibility to Lung Cancer
The purpose of this study is to help us better understand the cellular changes that may lead to the development of lung cancer. We want to compare people with a second primary lung cancer with those who have only a first primary lung cancer. We hope to use the information obtained in this study as the basis for future studies and will not regard the results from this study as final. We will analyze your blood cells and DNA to measure the changes in several genes that we believe may be involved in lung cancer. We also want to evaluate the capacity for your DNA to repair itself.
Checked against the public recordLast updated Mar 29, 2023 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Not specified
- Study type
- Observational
- Phase
- Not applicable
- Sponsor
- Memorial Sloan Kettering Cancer Center
- Interventions being studied
- Other: Blood draw and Questionnaires; Other: Blood draw and Questionnaires
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
Inclusion Criteria: * Cases will be eligible for inclusion if: * They have been diagnosed with a second primary lung cancer, and * They speak English or a language for which we have a translated consent form, and * They understand and agree to sign informed consent, and * They agree to give us a blood sample, and * They agree to give us a tissue sample when part of normal clinical procedures, and * They agree to complete the study questionnaires, and * They agree to have their pathology information reviewed. This could include biopsy specimens. Controls will be eligible for inclusion if * They have been diagnosed with a first primary lung cancer, and * They speak English or a language for which we have a translated consent form, and * They understand and agree to sign informed consent, and * They agree to give us a blood sample, and * They agree to give us a tissue sample when part of normal clinical procedures, and * They agree to complete the study questionnaires, * They agree to have their pathology information reviewed. This will could include biopsy specimens. Exclusion Criteria: * Subjects who do not meet the inclusion criteria as either cases or controls will not be eligible for this study. * Control subjects who have a history of another cancer, other than nonmelanoma skin cancer or a first primary lung cancer, will not be eligible for this study. * Control subjects who otherwise meet the eligibility requirements above but who have had chemotherapy and/or are currently being treated with chemotherapy will be excluded from the functional assay, but not from the genotyping.
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- Memorial Sloan Kettering Cancer CenterNew York, New York
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Mar 29, 2023. Always confirm current availability with the study team.