Adjuvant Cisplatin and Docetaxel in Non Small Cell Lung Cancer
* To determine if docetaxel and cisplatin can be administered in a dose intense manner in the adjuvant setting in resected non-small cell lung cancer * To evaluate the time to progression and overall survival * To evaluate toxicities of this chemotherapy combination in the adjuvant setting * To correlate XPD and ERCC1 polymorphisms with time to progression and toxicities in patients treated with this regimen
Checked against the public recordLast updated Nov 19, 2019 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Treatment
- Study type
- Interventional
- Phase
- Phase 2
- Sponsor
- University of Wisconsin, Madison
- Interventions being studied
- Drug: docetaxel and cisplatin
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
Inclusion Criteria: * Stage IB to IIIA non-small cell lung cancer completely resected within 4 to 8 weeks of initiating treatment on study * Performance Status ECOG 0 or 1 * Peripheral neuropathy: \< grade 1 * Adequate blood cell counts * Adequate liver and hepatic function * Women of childbearing potential must have a negative pregnancy test. * Men and women of childbearing potential must be willing to consent to using effective contraception while on treatment and for at least 3 months thereafter Exclusion Criteria: * Patients with a history of severe hypersensitivity reaction to Docetaxel® or other drugs formulated with polysorbate 80. * Women who are breast-feeding. * Coexistent second malignancy or history of prior malignancy within previous 5 years (excluding basal or squamous cell carcinoma of the skin that has been treated curatively) * Uncontrolled cardiac disease or uncontrolled hypertension
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- University of Wisconsin Comprehensive Cancer CenterMadison, Wisconsin
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Nov 19, 2019. Always confirm current availability with the study team.