Spectroscopy With Surface Coils and Decoupling

Study summary

The purpose of this study is to obtain chemical information from part of your body without a biopsy. This is done using a technique called magnetic resonance spectroscopy (MRS) which is similar to magnetic resonance imaging (MRI) except that signals are detected from the chemicals (spectroscopy) naturally present in your body using radio waves. To receive this information from your body, small loops of wire (surface coils), placed near the tissue of interest, may be used to more effectively detect signals that come from the chemicals in your body. The investigators may use a second radio channel simultaneously, which will allow us to obtain greater chemical information (decoupling). The results may also help us to understand how this study can be used to help other patients with your condition.

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Key things to know

Main goalDiagnostic

This describes the study’s primary purpose.

What is being studiedProton-decoupled 31P MRS at 1.5T and 1H Spectroscopy at 1.5T and 3T

The study team can explain what participation involves.

Who it may be forAdrenal Cortical Cancer · Brain Cancer

These are broad labels—not an eligibility decision.

Checked against the public recordLast updated Dec 28, 2015 · Source: ClinicalTrials.gov

Is enrollment open?Completed

Ask the study team to confirm whether enrollment is open.

What kind of study?Phase 1

Interventional

Where is it offered?1 U.S. location

Locations may change over time.

Who runs it?Memorial Sloan Kettering Cancer Center

Study sponsor

Study overview

What this study is about

Purpose: Diagnostic
Study type: Interventional
Phase: Phase 1
Sponsor: Memorial Sloan Kettering Cancer Center
Interventions being studied: Device: Proton-decoupled 31P MRS at 1.5T; Device: 1H Spectroscopy at 1.5T and 3T

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How this study is categorized

These labels come from structured fields and exact terms in the public record.

Public criteria

Who may be able to participate

The sponsor separates these requirements into two groups. You do not need to interpret them alone—use them to guide a conversation with the study team.

Requirements people may need to meetInclusion criteria

Patients must have suspected or documented neoplastic disease, strongly suspected or established by physical examination, history or conventional histologic biochemical or imaging techniques, or have surgical or aspiration biopsy that will be used to establish a diagnosis
Patients with obstructive jaundice, both from malignant and non-malignant disease, will be considered for the study
Patients/volunteers must be clinically stable and not require cardiovascular monitoring
Patients must be 6 years of age or older and be able to cooperate for an approximately 60 minute examination
Volunteers must be 18 years of age or older

Reasons someone may not be able to joinExclusion criteria

Inability to cooperate for an MR exam
Contraindication to MR: Pacemaker, Aneurysmal clips Any ferrous metallic implants which could be deflected by the magnet, Metal implants in field of view, Pregnant women, OR Age and mental status wherein he/she is unable to cooperate for MR study

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

Study sites

U.S. locations

Memorial Sloan-Kettering Cancer CenterNew York, New York

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Dec 28, 2015. Always confirm current availability with the study team.

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