CompletedPhase 1NCT00328562

ZD1839 With Hypofractionated Radiation Therapy With an Immobilization Device for Advanced Non-Small Cell Lung Cancer

The purpose of this study is to determine the safety and effectiveness of Iressa when used with a short course of high dose radiation therapy in patients with lung cancer.

Checked against the public recordLast updated May 4, 2025 · Source: ClinicalTrials.gov

StatusCompleted
PhasePhase 1
U.S. locations1
SponsorSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
01
Study overview

What this study is about

Purpose
Treatment
Study type
Interventional
Phase
Phase 1
Sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Interventions being studied
Drug: ZD1839 (Iressa); Radiation: Thoracic Radiotherapy
02
Explore related studies

How this study is categorized

These labels come from structured fields and exact terms in the public record.

03
Public criteria

Who may be able to participate

Inclusion Criteria: * Histologically confirmed non small cell lung cancer * Stage IV needing radiation therapy to control symptoms * Patients with brain metastases * Unresectable or medically inoperable Exclusion Criteria: * Small cell lung cancer * Previous thoracic radiation therapy * Oxygen-dependent patients * Forced expiratory volume in 1 second (FEV1) less than 1.5 * Patients with active interstitial lung disease * Patients with underlying lung disease

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

04
Study sites

U.S. locations

  • Thomas Jefferson University HospitalPhiladelphia, Pennsylvania

Source and freshness
Processed from ClinicalTrials.gov. Last public update: May 4, 2025. Always confirm current availability with the study team.

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