TerminatedPhase 3NCT00300495

Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung Resection

Atrial fibrillation is a very common complication of pulmonary resection. Patients who develop atrial fibrillation require additional treatment and are more likely to stay in the hospital for longer period of time increasing the costs associated with the operation. We propose a randomized controlled trial to see if oral amiodarone given for one week before surgery can prevent atrial fibrillation after pulmonary resection. We plan to evaluate the incidence of atrial fibrillation in patients who received preoperative amiodarone and compare them to the incidence of atrial fibrillation in patients who did not received preoperative amiodarone.

Checked against the public recordLast updated Apr 28, 2017 · Source: ClinicalTrials.gov

StatusTerminated
PhasePhase 3
U.S. locations1
SponsorBeth Israel Deaconess Medical Center
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Study overview

What this study is about

Purpose
Prevention
Study type
Interventional
Phase
Phase 3
Sponsor
Beth Israel Deaconess Medical Center
Interventions being studied
Drug: Amiodarone; Other: Control arm, standard care
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How this study is categorized

These labels come from structured fields and exact terms in the public record.

Treatment approach
03
Public criteria

Who may be able to participate

Inclusion Criteria: * Resectable lung nodule or mass Exclusion Criteria: * Allergy to amiodarone * Currently taking amiodarone * Documented atrial fibrillation within past 12 months * Known pulmonary fibrosis * Known hepatic dysfunction * Thyroid disease * 2nd or 3rd degree heart block * Severe SA node disease * Bradycardia-induced syncope * Pregnancy

Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.

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Study sites

U.S. locations

  • Beth Israel Deaconess Medical CenterBoston, Massachusetts

Source and freshness
Processed from ClinicalTrials.gov. Last public update: Apr 28, 2017. Always confirm current availability with the study team.

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