Real-Time Image Guided Lymphatic Mapping and Nodal Targeting in Lung Cancer

Inclusion Criteria: * Suspected or histologically documented new non-small cell carcinoma that have agreed to undergo a thoracotomy for segmentectomy, lobectomy, bilobectomy or pneumonectomy as recommended by their thoracic surgeon for treatment * Surgically resectable lung cancer * N2 lymph nodes negative on PET scan or mediastinoscopy * Age \> or equal to 18 years of age * Men, women of non-child bearing age or women with a negative pregnancy test Exclusion Criteria: * Patient does not want to undergo subsequent surgical resection * Medical condition such as uncontrolled infection or cardiac disease that, i the opinion of the treating surgeon, makes resection unreasonably hazardous for the patient. * T4 or N2 disease * Pre-operative spirometry that suggests they cannot undergo resection of their primary tumor by segmentectomy, lobectomy, bilobectomy, or pneumonectomy * Iodide or seafood allergy * Pregnant or lactating women