Fluorescent Light Bronchoscopy Plus White Light Bronchoscopy for Early Detection of Lung Cancer
RATIONALE: Fluorescent bronchoscopy, when used in combination with conventional white light bronchoscopy, may improve the ability to detect early lung cancer. PURPOSE: A pilot study to evaluate fluorescent light bronchoscopy plus conventional bronchoscopy as a tool for screening and detecting lung cancer in persons with completely resected head and neck cancer or successfully treated early-stage lung cancer.
Checked against the public recordLast updated Apr 29, 2015 · Source: ClinicalTrials.gov
What this study is about
- Purpose
- Screening
- Study type
- Interventional
- Phase
- Not applicable
- Sponsor
- National Cancer Institute (NCI)
- Interventions being studied
- Other: cytology specimen collection procedure; Other: immunohistochemistry staining method; Other: sputum cytology; Procedure: bronchoscopic and lung imaging studies; Procedure: bronchoscopy; Procedure: comparison of screening methods; Procedure: endoscopic biopsy
How this study is categorized
These labels come from structured fields and exact terms in the public record.
Who may be able to participate
DISEASE CHARACTERISTICS: * The following diagnoses are eligible: * Known or suspected bronchogenic carcinoma scheduled for bronchoscopy as part of standard diagnostic or staging work-up * Completely resected stage I/II non-small cell lung cancer with no evidence of metastasis * Stage III non-small cell lung cancer with no evidence of disease for at least 2 years following treatment * Small cell lung cancer with no evidence of disease for at least 2 years following treatment * Completely resected head and neck cancer with no evidence of metastasis * Ability to produce sputum samples required PATIENT CHARACTERISTICS: Age: * 18 and over Performance status: * ECOG 0-2 Hematopoietic: * WBC 2,000-20,000 * Platelets at least 50,000 Hepatic: * Not specified Renal: * Not specified Cardiovascular: * No uncontrolled hypertension (i.e., systolic pressure greater than 200 mm Hg or diastolic pressure greater than 120 mm Hg) * No unstable angina Other: * No bleeding disorder * No allergic reaction to topical lidocaine * No pregnant women PRIOR CONCURRENT THERAPY: Biologic therapy * Not specified Chemotherapy * Not specified Endocrine therapy * Not specified Radiotherapy * At least 18 months since ionizing radiotherapy to the chest Surgery * See Disease Characteristics Other * At least 1 month since yttrium-aluminum-garnet (YAG) laser therapy to the lung * At least 3 months since fluorescent photosensitizing drugs (e.g., Photofrin)
Important: This is the sponsor’s public criteria, not a determination of eligibility. The study team must review your individual situation.
U.S. locations
- Warren Grant Magnuson Clinical Center - NCI Clinical Studies SupportBethesda, Maryland
Source and freshness
Processed from ClinicalTrials.gov. Last public update: Apr 29, 2015. Always confirm current availability with the study team.